Raynaud’s phenomenon results from a vasospasm that significantly reduces blood flow to the fingertips (and toes) causing them to turn white in response to cold or emotional stress. Chronic, recurring episodes of Raynaud’s phenomenon can result in atrophy of the skin and subcutaneous tissues and on rare occasions can cause ulceration/ischemic gangrene.
A recent evidence-based article on Raynaud’s Disease has free access here and a longer article on Comprehensive Management of Raynaud’s Syndrome by WH Merritt can be found in Clin Plast Surg. 1997 Jan;24(1):133-59.
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